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NuGen Unique Dual Index Pairs

NuGen Technologies has added 96 unique dual index pairs to several of its library preparation kits. The index pairs enable software to detect when so-called "barcode hopping" has occurred. As a result, they prevent sequence reads from being assigned to the wrong sample. Dual index pairs are currently available for the Ovation Ultralow System V2 for DNA-seq library preparation and for the Universal Plus mRNA-Seq and Trio RNA-Seq systems for RNA-Seq library preparation. They will also be available for the Methyl-Seq product line soon.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.