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Norgen Small RNA Library Prep Kit and Sequencing Services

Norgen Biotek, based in Ontario, has launched a Small RNA Library Prep Kit for Illumina sequencing instruments as well as sequencing services on Illumina instruments. The Small RNA Library Prep Kit needs between 0.5 nanograms and 1 nanogram of input RNA and can process samples from plasma, serum, blood, cerebral spinal fluid, urine, and exosomes, according to the company. Turnaround time is less than five hours. Norgen also offers complementary products, including NGS-compatible cel-miR-39 spike-in and an NGS library quantification kit. The services Norgen launched include isolation, library prep, sequencing, and bioinformatics. Sequencing can be performed on Illumina's MiSeq or NextSeq 500 instruments and includes small RNA-seq, RNA-seq, 16S metagenomics, targeted DNA or RNA sequencing, exome sequencing, and whole-genome sequencing.  

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.