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New England Biolabs' NEBNext Direct Cancer HotSpot Panel

New England Biolabs, or NEB, has launched the NEBNext Direct Cancer HotSpot Panel. The new panel incorporates a novel targeted enrichment technology for next-generation sequencing, NEBNext Direct, that was developed in collaboration with Directed Genomics, the company said. The new technology leverages NEB's deep expertise in enzymology to maximize yields and minimize errors that can be introduced during sample preparation. The Cancer HotSpot panel combines the strength of both PCR amplicon and hybridization based approaches to employ a single tube, single day workflow that combines enrichment with library preparation. It enriches critical regions within 50 commonly studied genes known to be associated with cancer.

The Scan

Gap in COVAX Doses

BBC News reports that COVAX is experiencing a vaccine shortfall, as the Serum Institute of India has paused exports.

Sanofi, GSK Report Promising Results

The Wall Street Journal reports that the candidate SARS-CoV-2 vaccine from Sanofi and GlaxoSmithKline has had encouraging early results.

Influence of Luck

The New York Times examines how the US avoided variant-fueled increases in COVID-19 cases.

PLOS Papers on Retina GWAS, Hantaan Virus, COVID-19 Phenome-Wide Association Study

In PLOS this week: genome-wide association study of retinal morphology, analysis of hantaan virus found in a mouse, and more.