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New England Biolabs' NEBNext Direct Cancer HotSpot Panel

New England Biolabs, or NEB, has launched the NEBNext Direct Cancer HotSpot Panel. The new panel incorporates a novel targeted enrichment technology for next-generation sequencing, NEBNext Direct, that was developed in collaboration with Directed Genomics, the company said. The new technology leverages NEB's deep expertise in enzymology to maximize yields and minimize errors that can be introduced during sample preparation. The Cancer HotSpot panel combines the strength of both PCR amplicon and hybridization based approaches to employ a single tube, single day workflow that combines enrichment with library preparation. It enriches critical regions within 50 commonly studied genes known to be associated with cancer.

The Scan

Back as Director

A court has reinstated Nicole Boivin as director of the Max Planck Institute for the Science of Human History, Science reports.

Research, But Implementation?

Francis Collins reflects on his years as the director of the US National Institutes of Health with NPR.

For the False Negatives

The Guardian writes that the UK Health Security Agency is considering legal action against the lab that reported thousands of false negative COVID-19 test results.

Genome Biology Papers Present Epigenetics Benchmarking Resource, Genomic Architecture Maps of Peanuts, More

In Genome Biology this week: DNA methylation data for seven reference cell lines, three-dimensional genome architecture maps of peanut lines, and more.