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New England Biolabs Monarch Genomic DNA Purification Kit

New England Biolabs has launched the Monarch Genomic DNA Purification Kit for high-yield purification of high-molecular-weight DNA fragments (peak size greater than 50 kb), making it ideal for use upstream of long-read sequencing platforms. The inclusion of RNase A, optimized protocols, and buffer chemistry enable researchers to prevent RNA contamination (RNA levels are generally less than 1 percent) and address a wide variety of sample types without having to purchase any specialized kits, NEB said.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.