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NeoLAB Solid Tumor Monitor and BTK Inhibitor Acquired Resistance Test

NeoGenomics has launched the NeoLAB Solid Tumor Monitor and NeoLAB Bruton Tyrosine Kinase (BTK) Inhibitor Acquired Resistance test. Each new test uses cell-free DNA from peripheral blood plasma to quantify and track genomic abnormalities in the tumors of cancer patients. Resistance to BTK inhibitors is associated with mutations in the BTK and PLCG2 genes. The test is capable of detecting mutations in these two genes prior to tissue or cell-based testing. The test can be used to monitor patients treated with BTK inhibitors, especially in chronic lymphocytic leukemia, mantle cell lymphoma, and diffuse large B-cell lymphoma, and to alert physicians to mutations in BTK and PLCG2 that may indicate early resistance to BTK inhibitor treatment.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.