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NeoGenomics Comprehensive Multimodality NeoTYPE

NeoGenomics has expanded its NeoTYPE tumor-specific profiling test menu to include new profiles for head and neck tumors, pancreatic cancer, liver cancer, sarcoma, and cancers of unknown primary (CUP). A complete analysis of somatic mutations in BRCA1 and BRCA2 are now a part of breast, ovarian, and pancreatic cancer profiling. All profiles now include analysis of PD-L1 expression by immunohistochemistry. In addition, HPV testing is being integrated with next-generation sequencing for head and neck cancer. The company is also offering profiling of sarcoma for chromosomal translocation using NGS and complete profiling of CUP using extensive immunohistochemistry, NGS of 315 genes, and nine fluorescence in situ hybridization probes. 

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.