NCBI RefSeq 74 | GenomeWeb

NCBI RefSeq 74

Jan 20, 2016

RefSeq 74 is now available via ftp and through the National Center for Biotechnology Information's programming utilities. This release incorporates genomic, transcript, and protein data available as of January 11, 2016 and includes 89,458,499 records, 56,496,614 proteins, 13,719,136 RNAs, and sequences from 57,993 organisms. Additional details are available in the release notes.

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GATC Biotech InView Human Exome Explore

GATC Biotech, a Constance, Germany-based sequencing services company has launched an exome sequencing service, InView Human Exome Explore. The service can be used for DNA from cells, blood, tissue, bacteria, yeast, fungi, and formalin-fixed paraffin-embedded tissue. Sequencing is performed under diagnostic standards and includes protocols for hard-to-capture exons. Customers also have the option of including Qiagen's Ingenuity Variant Analysis for biological interpretation. 

Dec 02, 2016

Cellecta Driver-Map Human Genome-Wide Expression Profiling Service

Cellecta has launched the Driver-Map human genome-wide expression profiling service, a targeted RNA expression method that enables quantitative expression analysis of all known 19,000 protein-coding genes in the human genome from as little as 10 pg of total RNA.

The method uses multiplexed RT-PCR directly from total RNA followed by next-generation sequencing, and employs a robust single-tube protocol with features that are particularly suitable to complex applications such as large-scale biomarker discovery and tumor microenvironment characterization. Cellecta noted that the method uses an optimized primer set that yields 1,000- to 10,000-fold dynamic range.

Dec 02, 2016

Leica Biosystems/Advanced Cell Diagnostics Aperio RNA ISH Algorithm

Leica Biosystems and Advanced Cell Diagnostics (a Bio-Techne brand) have announced the availability of the Aperio RNA ISH algorithm for use with ACD's RNAscope ISH assays.

This new offering builds on an existing collaboration between the companies to automate ACD's RNAscope assays on the Leica Biosystems BOND RX research staining platform. The new RNA ISH algorithm completes the automated RNA ISH workflow for researchers performing the RNAscope assay on the BOND RX, the companies said.

Dec 02, 2016

WaveSense nRichDx

WaveSense has launched the nRichDx system for bulk isolation of target cells and nucleic acids from liquid biopsies. The new system uses WaveSense's proprietary paramagnetic bead technology to capture circulating tumor cells and cell-free DNA or RNA in quantities sufficient for subsequent next-generation sequencing or PCR analysis. The system can capture cells and nucleic acids from an array of sample types including blood, urine, and bone marrow, and is specifically designed and optimized for high-volume, low-yield specimens, the company said.

Dec 02, 2016

CloudLIMS Lite

CloudLIMS.com has released a new version of its SaaS LIMS, CloudLIMS Lite to help biobanks and clinical, research, and testing laboratories keep track of their biospecimens from sample entry through labeling, storing, shipping and disposal. The new version is faster and more efficient product, allowing batch processing of data, inventory tracking, kit management, and centralized single-click operations coupled with an intuitive interface, the company said.

Dec 02, 2016

MyHeritage DNA Test for Genealogy

MyHeritage has launched MyHeritage DNA, a home testing kit for consumer genealogy testing. The kit consists of a cheek swab that is mailed to MyHeritage's lab for analysis. The user is then invited to view the results on the company's website.

In its initial version, the test provides two main features: detailed ethnicity reports that map the user's ethnic and geographic origins, and DNA matches for finding relatives. Additional features and capabilities are planned for the future. The initial reports currently include 25 ethnicities, but this will improve following MyHeritage's Founder Population project. In this project, the company picked more than 5,000 participants from its 85 million members, by virtue of their family trees exemplifying consistent ancestry from the same region or ethnicity for many generations. In the next few months, the project will yield a rich DNA data set of more than 100 ethnicities that will enable MyHeritage to show users their ancestral roots with far greater resolution than other services, the company said.

Dec 02, 2016

MNG Laboratories Carrier Exome

MNG Laboratories has introduced the MNG Carrier Exome, a test to determine carrier status for recessive disorders like cystic fibrosis, sickle cell anemia, and Tay-Sachs disease. The test is designed to detect a wide range of rare family or sub-population specific variants that could have an adverse effect in offspring. Whole exome sequencing is performed on both partners in order to detect shared known pathogenic and predicted disruptive variants in genes that are causative of autosomal recessive disorders. This test is intended for prospective parents who are interested in the most complete review of their genetic background to better understand their risk of having children with rare autosomal recessive disorders. It is not recommended for diagnostic purposes.

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Dec 01, 2016

ArcherDx Immunoverse

ArcherDx has launched Archer Immunoverse, a suite of immune repertoire sequencing assays. The targeted panels analyze RNA using Archer's patented Anchored Multiplex PCR (AMP) chemistry for open-ended amplification from molecular barcoded adaptors and next-generation sequencing to characterize the immune repertoire. After sequencing, the Immune Repertoire pipeline is used to identify clonotypes. The workflow requires less than 3.5 hours of hands-on time and between 25 nanograms and 2 micrograms of input RNA from peripheral blood mononuclear cells, formalin-fixed paraffin-embedded tissue, or fresh frozen tissue.

Nov 30, 2016

Phenomenex Clarity LC Columns for Synthetic Oligo Analysis

Phenomenex has launched two new products for characterization and purification of synthetic oligonucleotides, the Clarity Oligo-XT C18 column and the Clarity Oligo-SAX column.

The products will be offered as part of the firm's Clarity BioSolutions portfolio of columns for chromatographic analysis.

The Oligo-XT C18 column is intended for high-efficiency reversed-phase liquid chromatography analysis and purification. Featuring new and robust core-shell media, it offers the separation power to resolve closely related synthetic oligos and the sensitivity to improve quantitation by mass spectrometry. The columns are available in directly scalable 1.7-micrometer, 2.5-micrometer, and 5-micrometer particle sizes. 

The Oligo-SAX is a high-resolution strong anion exchanger for characterization, featuring new rugged non-porous particles for improved column lifetimes. It is engineered for performance at high pH and temperatures up to 85° C. It comes in a 5-micrometer particle size for analytical characterization.

Nov 23, 2016

NextGene 2.4.2

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