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Ncardia DiscoverHit Drug Screening Platform

Ncardia has launched the DiscoverHit drug screening platform, a service intended to help researchers access disease-relevant biology earlier in the drug-discovery process. DiscoverHit is a phenotypic drug screening platform comprising genetic and induced human pluripotent stem cell-derived cardiac and neural disease models; controlled bioreactor-based manufacturing to enable batch sizes compatible with high-throughput screening; customized development of disease-relevant assays; and high-throughput screening combined with high-content data acquisition and analysis.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.