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NanoString CAR-T Characterization Panel

NanoString Technologies has announced the launch of a new gene expression panel for the molecular characterization of CAR-T cells in research, development, and manufacturing of adoptive cell therapies. According to the company, the new nCounter(R) CAR-T Characterization Panel was created in collaboration with eight academic centers and is designed for use across the entirety of the CAR-T workflow including leukapheresis, manufacturing, and post-infusion monitoring.

The customizable 780-gene expression panel incorporates content to measure eight essential components of CAR-T cell biology including T-cell activation, metabolism, exhaustion, and receptor diversity with optional customization for measuring transgene expression with NanoString's Protein Barcoding Service. The firm expects to begin shipping the panel in December.

The Scan

Possibly as Transmissible

Officials in the UK say the B.1.617.2 variant of SARS-CoV-2 may be as transmitted as easily as the B.1.1.7 variant that was identified in the UK, New Scientist reports.

Gene Therapy for SCID 'Encouraging'

The Associated Press reports that a gene therapy appears to be effective in treating severe combined immunodeficiency syndrome.

To Watch the Variants

Scientists told US lawmakers that SARS-CoV-2 variants need to be better monitored, the New York Times reports.

Nature Papers Present Nautilus Genome, Tool to Analyze Single-Cell Data, More

In Nature this week: nautilus genome gives peek into its evolution, computational tool to analyze single-cell ATAC-seq data, and more.