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MRC Holland SALSA digitalMLPA

MRC Holland has released SALSA digitalMLPA, a novel technique that enables the simultaneous detection of up to 1,000 copy number variants. It combines MRC Holland's proprietary Multiplex Ligation-dependent Probe Amplification (MLPA) technology for target amplification with next-generation sequencing, using the company's Coffalyser digital MLPA analysis software. Up to 192, and soon up to 384, digitalMLPA samples can be analyzed in parallel. The first digitalMLPA assay available is D001 Hereditary Cancer Panel 1, which targets 28 genes associated with various hereditary cancers.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.