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MRC Holland SALSA digitalMLPA

MRC Holland has released SALSA digitalMLPA, a novel technique that enables the simultaneous detection of up to 1,000 copy number variants. It combines MRC Holland's proprietary Multiplex Ligation-dependent Probe Amplification (MLPA) technology for target amplification with next-generation sequencing, using the company's Coffalyser digital MLPA analysis software. Up to 192, and soon up to 384, digitalMLPA samples can be analyzed in parallel. The first digitalMLPA assay available is D001 Hereditary Cancer Panel 1, which targets 28 genes associated with various hereditary cancers.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.