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Molecular Health's Clinical Decision Support Solutions

Molecular Health has launched two new clinical decision support solutions, Molecular Health Guide Workbench Manager and Molecular Health Guide Clinical Annotation Service. These services are based on Dataome, Molecular Health's proprietary cloud-based software platform for the automated analysis, clinical interpretation, and reporting of genetic alterations from next-generation sequencing-based tests. 

The Workbench Manager offers tools for analyzing patient's tumor data and generating custom reports. These reports cover actionable variants and summarize potentially effective and ineffective treatment options as well as treatments that may pose a higher risk of adverse reactions to patients. The software also provides a tool for matching patients to clinical trials. 

The Clinical Annotation Service enables automated delivery of clinically-reviewed annotations for actionable variants. Through the service, Molecular Health provides clinicians with clinical variant narratives, evidence-based treatment options, matching trials, and other supplemental data such as drug descriptions and drug-drug interactions. The technology can be integrated into existing workflows, pipeline management, and reporting systems for use by high-throughput laboratories and other high-volume customers.

The Scan

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.

Estonian Biobank Team Digs into Results Return Strategies, Experiences

Researchers in the European Journal of Human Genetics outline a procedure developed for individual return of results for the population biobank, along with participant experiences conveyed in survey data.

Rare Recessive Disease Insights Found in Individual Genomes

Researchers predict in Genome Medicine cross-population deletions and autosomal recessive disease impacts by analyzing recurrent nonallelic homologous recombination-related deletions.

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.