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Mission Bio Tapestri, Panels

Apr 17, 2018

Mission Bio has updated its Tapestri single-cell DNA analysis platform, which is now compatible with the Illumina HiSeq 2500 sequencer to allow for multiplexing and larger panels.

The company has also launched two new panels for myeloid disorders and for solid tumor profiling. The Tapestri Single-Cell DNA Myeloid Panel, designed to cover several myeloid disorders, targets single-nucleotide variants and indels in 47 genes. The Tapestri Single-Cell Tumor Hotspot Panel targets SNV and indel hotspot mutations across 50 genes involved in different solid tumor types and has been tested with breast, lung, prostate, and colorectal cancer nuclei from fresh-frozen tissue samples.

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Oct 20, 2019

Sophia Genetics Whole Exome Solution

Sophia Genetics has released a new version of Sophia Whole Exome Solution, which the company said reduces turnaround time for analysis of whole-exome sequences. The updated Sophia WES now features detection of copy-number variations at a resolution of two to five exons without the need for a reference sample. The product also supports analysis of variants in familial trios to filter variants based on different inheritance modes. 

Oct 17, 2019

Illumina Infinium Global Diversity Array

Illumina has launched the Infinium Global Diversity Array, the commercial version of the array designed for use in the National Institutes of Health All of Us research program. The array features about 1.9 million variants, including imputation-optimized tag SNPs and up-to-date clinical research content from public databases such as ClinVar, the National Human Genome Research Institute-EBI database, and Pharmacogenomics Knowledgebase (PharmGKB). The array has broad utility for a variety of large-scale screening and association studies, with content relevant for polygenic risk scoring, common-disease association studies, and inherited risk screening, Illumina said. In addition, the array offers extremely high genomic coverage and imputation performance across 26 diverse populations. It comes in an eight-sample format chip that has room to add up to 175,000 custom beadtypes, the company said.

Oct 17, 2019

Integrated DNA Technologies NGS Discovery Pools

Integrated DNA Technologies this week launched its NGS Discovery Pools, individually synthesized, 5'-biotinylated oligo pools designed to enable researchers to rapidly build custom panels at a fraction of the cost compared to conventional panels. According to the firm, the NGS Discovery Pools offer the quality of individual synthesis at a speed and scale needed for discovery in precision medicine. It also noted that the new pools will enable its customers to use its "high-quality capture technology for smaller projects and in earlier stages where content may still be changing, allowing for a smooth transition to Lockdown Probes as projects are scaled up and validated for clinical use." The firm's xGen Lockdown Probes are already commercially available for target capture in clinical sequencing applications.

Oct 17, 2019

Living DNA Genealogy and Wellbeing Kits

Living DNA has launched two new kits to provide customers with genealogy and wellbeing information. The company's $49 or £49 Starter DNA Kit is designed for individuals who are interested in DNA testing but are unsure about what type of test to take, the company said. Using a mouth swab sample, it provides a high-level global view of a customer's ancestry, the ability to find DNA matches with others worldwide, and wellbeing reports focused on supporting diet and exercise. The company's $129 or £129 Wellbeing Kit, meantime, provides detailed reports including lifestyle-related advice on vitamin levels and deficiencies, metabolism, response to food components such as glucose and lactose, and fitness and exercise response. The new offerings join Living DNA's existing $99/£99 Ancestry Kit.

Oct 17, 2019

Thermo Fisher Scientific Acrometrix BCR-ABL panel

Thermo Fisher Scientific has launched its Acrometrix BCR-ABL Panel. According to Thermo Fisher, the panel is intended to be used as an external control panel for analytical validation of BCR-ABL test methods. The firm said that the research-use-only panel can monitor assay performance at every clinical stage due to its expanded dynamic range.

Oct 16, 2019

iGenomX Riptide High-Throughput Rapid Library Preparation Workflow

iGenomX has launched its Next Generation Genotyping (NGG) application for population-scale research, including its Riptide High-Throughput Rapid Library Preparation (HT-RLP) system. The firm said that NGG allows researchers to analyze more than 10 times the number of genetic variants for a fraction of the cost per sample. Specifically, iGenomX's HT-RLP will allow scientists to perform sequence-based genotyping across more than 37 million genetic markers for less than $80 per sample, including sequencing and analysis. 

Oct 16, 2019

Nonacus ExomeCG Exome Capture Kit

Nonacus of Birmingham, UK, has launched ExomeCG, a "clinically enhanced" exome capture kit that is designed to enable whole-exome sequencing and targeted copy number analysis in a single assay. According to the company's website, the kit provides CNV detection at loci known to have both gene- and exon-level rearrangements, which enables researchers to replace array- and MLPA-based CNV analyses. Codeveloped with bioinformatics firm Congenica, ExomeCG can be used in combination with that company's clinical decision support platform to interpret next-generation sequencing data for clinical decision making, Nonacus said.

Oct 16, 2019

TriLink Biotechnologies CleanTag Primer Sets

TriLink Biotechnologies has introduced two new primer sets for its CleanTag kit. The Ion Torrent Convert barcode primer sets allow small RNA library preparation on Thermo Fisher Scientific's sequencing platform. According to TriLink, CleanTag includes modified adapters that block adapter-dimer formation. The firm said that CleanTag uses automated, bead-based separation to allow a simplified, cleaner workflow, retaining high sensitivity, and the ability to work with low-abundance RNA input as well as at the single-cell level. Primers in each index set for Ion Torrent include the RT primer, 12 indexed forward-PCR primers, and a reverse-PCR primer. 

Oct 16, 2019

Gencove Low-Pass Sequencing & Analysis Software Service

Gencove has launched its low-pass sequencing platform. The firm said that the cloud-based system supports human, agricultural, companion animal, and model organism applications. 

Oct 16, 2019

New England Biolabs NEBNext Direct Genotyping Solution

New England Biolabs has launched the NEBNext Direct Genotyping Solution, a capture-based approach for high-throughput genotyping in ag-bio applications. The new kit, for use with next-generation sequencing, uses highly multiplexed, capture-based enrichment to deliver automatable genotyping in a single day. The product can be used with 100 to 5,000 markers, features pre-capture multiplexing of up to 96 samples, and allows for more than 3.8 million genotypes in a single Illumina sequencing run.

Oct 15, 2019

HTG Molecular HTG EdgeSeq Autoimmune Panel

HTG Molecular said it is now taking orders for its new HTG EdgeSeq Autoimmune Panel, which it expects to commercially launch in kit form or as a service at the end of October. The firm said it has designed the panel to address questions around autoimmune disorders, as well as for examining immune system dysfunction, discovering new biomarkers, and discovering predictive signatures of drug responses in the autoimmune space. 

Oct 15, 2019

Magbio Genomics HighPrep Total RNA Plus Kit

Magbio Genomics has successfully developed the HighPrep Total RNA Plus Kit, a RNA purification chemistry for Mawi DNA Technologies' iSwab-RNA-V2 collection tool. According to Mawi, researchers isolating RNA from iSwab-RNA-v2 using HighPrep will have high-quality RNA yield in the range of 1-4 µg per sample. In addition, Mawi said that both tools can be fully automated on industry platforms including the Hamilton MicroLabStar. 

Oct 15, 2019

Paragon CleanPlex Hereditary Cancer Panel V2

Paragon Genomics has launched its CleanPlex Hereditary Cancer Panel V2. The Haywood, California-based firm said that updated version of the platform halves the number of required primer pools, reducing the required DNA sample size and further increasing ease of use. 

Oct 15, 2019

Qiagen QIAseq FastSelect RNA Removal Products

Qiagen has launched the QIAseq FastSelect -rRNA and -Globin HMR Kits, which are designed to remove more than 97 percent of ribosomal RNA and globin messenger RNA from human, mouse, and rat samples to optimize RNA sequencing.

Qiagen also launched the QIAseq FastSelect 5S/16S/24S Kit to remove abundant bacterial 5S/16S/24S rRNA from RNAseq libraries prepared from complex microbial communities in soil, water, stool, and sludge samples.

The company noted that its QIAseq FastSelect kits remove unwanted RNA with a single 10-second pipetting step and 14 minutes of incubation.

Oct 15, 2019

Loop Genomics Transcriptomics Service

Loop Genomics has launched a targeted, long-read, single-cell transcriptomics service that couples Illumina sequencing instruments with probe capture and cDNA from single cells to generate long-read data. The service includes Loop's computational pipeline that reconstructs the long-read transcripts from clouds of barcoded short reads and provides researchers with actionable reports, the company said.

New research shows that scientists need to do a better job of including a wider diversity of African genomes in their analyses, STAT says.

A new paper in Science shows that men are still winning a large majority of the most sought-after NIH grants.

Nature Research and the Estée Lauder Companies are awarding efforts to encourage girls to pursue careers in the STEM fields.

In Science this week: beneficial genetic variants inherited from archaic Neanderthal and Denisovan hominins, and more.

Oct
21
Sponsored by
Agilent

Genomics is a key element in the potential of precision medicine to transform oncology. 

Oct
23
Sponsored by
Swift Biosciences

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries. 

Oct
24
Sponsored by
Sunquest

This webinar will tell the story of Versiti’s journey in transforming genetic testing from a manual to a digitized process. It will include detail on how the organization succeeded, pain points along the way, a novel approach to variant assessment, and future plans for the program.

Oct
31
Sponsored by
PerkinElmer

This webinar will provide an overview of how the Center for Applied Genomics at Children's Hospital of Philadelphia has optimized its next-generation sequencing (NGS) workflow using a combination of PerkinElmer's Sciclone automation technology and target capture chemistry from Twist Bioscience.