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Menarini Silicon Biosystems CellMag Product Line

Menarini Silicon Biosystems has launched its CellMag product line. The line includes the CTC Epithelial Cell kit for ferrofluid-based EpCAM-positive circulating tumor cell enrichment, a magnetic tool, and consumables. The firm believes the product line will help researchers conduct specific, established, and standardized immunomagnetic enrichment and staining of CTCs in peripheral blood. After positive selection of enriched cells, performed by capturing cells through ferrofluids labeled with antibodies targeting specific antigens, the staining procedure delivers cells that are ready for enumeration, isolation, and downstream analysis. Menarini said the CellMag line provides researchers with a manual system using the same ferrofluid technology offered by its CellSearch system.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.