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MDNA Prostate Mitomic Test

Helomics and MDNA Life Sciences have launched MDNA's Prostate Mitomic Test, a liquid biopsy test for early detection of high-grade prostate cancer independent of prostate-specific antigen and age. The test utilizes the company's Mitomic technology platform which exploits unique biologic characteristics of mitochondrial DNA and has a high negative predictive value which can be used to help clinicians determine which patients have a high-grade tumor that requires immediate intervention, the company said. The laboratory-developed test will be available exclusively through Helomics' clinical lab.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.