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Macrogen: Northeast Asia Reference Database

Macrogen of Korea has released the Northeast Asian Reference Database (NARD). It includes whole-genome sequencing and genetic variant data for a panel of 1,779 individuals, including 850 Koreans, 384 Mongolians, 396 Japanese, 91 Chinese, and 58 Hong Kong residents, making it the largest reference panel representing those countries, according to the company. Macrogen expects the database will help improve the accuracy of imputation in genome-wide association studies and predict disease based on polygenic risk scores. Early next year, the company plans to release a second reference panel, from 10,000 individuals.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.