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Loop Genomics SARS-CoV-2 Long-Read Sequencing Service

Loop Genomics has launched a service for sequencing SARS-CoV-2, the virus that causes COVID-19, using long amplicons and synthetic long reads linked by universal molecular identifiers.

The service provides reads averaging 6 kb to 7 kb using only Illumina's short-read next-generation sequencing platform. The SARS-CoV-2 has a genome of approximately 30 kb. Along with consensus error correction, the technology allows researchers to characterize highly similar strains that have mutations thousands of bases apart.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.