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Loop Genomics Long Read Microbiome Sequencing Service

Loop Genomics has launched a new service for linked read microbiome sequencing for studies with large cohorts. For labs running at least 200 to 1,000 samples, Loop is offering 16S sequencing at a price between $38 and $20 per sample, depending on volume. Loop generates long reads using Illumina's short-read sequencing platform. The firm said it can deliver 40-fold lower error rates and can eliminate false positives, delivering species- and sometimes strain- level taxonomy.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.