LGC Seracare Seraseq Oncology Reference Controls

LGC Seracare has added four new products to its somatic cancer reference control portfolio. The Seraseq MSI Reference Panel Mix AF5% and AF20% are the company's first microsatellite instability reference materials that target the lengths of the regions commonly referred to as BAT-25, BAT-26, NR-21, NR-24, and MONO-27. These markers are blended at two different allele frequency levels (5 percent and 20 percent) to support MSI assay limit of detection determinations and accurate analysis of MSI status of patient samples.

The Seraseq NTRK Fusion RNA Mix is a 15-plex RNA mix of NTRK fusion genes that are important in next-generation sequencing assay evaluation of cancer patients harboring NTRK fusions for therapeutic intervention. This new product complements LGC Seracare's existing 15-plex FFPE NTRK reference material.

The Seraseq Compromised FFPE WT (DNA/RNA) RM is a more "patient-like (compromised)" negative sample control in FFPE format. A single FFPE section offers both RNA and DNA for targeted NGS assay validation and/or routine use in clinical testing. This product is complementary to the recently released Seraseq TNA WT (DNA/RNA) as well as mutation-positive Seraseq DNA and RNA reference materials, the company said.

All products are available in purified and FFPE formats, the company said.