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LGC High-Throughput Liquid Handling for PCR

LGC has launched the Meridian2 liquid dispensing system, a non-contact, on-the-fly dispenser suited to a wide range of dispensing applications, including reagents for genotyping and standard PCR. The Meridian2 features two plate positions for enhanced efficiency, integrated barcode reading, and automated assay mixing. It integrates into laboratories with existing SNPline automation or other Meridian instruments. The platform accurately dispenses 1-μL volumes into a 1,536-well plates in less than 45 seconds, with a CV of less than 5 percent, and the vacuum-based aspiration system allows multi-plate dispense for increased efficiency.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.