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Lexogen's Mix² software

Lexogen has launched the Mix² software, a tool for quantifying transcript isoforms in data from RNA-sequencing experiments. Features include accurate detection of differential expression, repeatable concentration estimates accross variable conditions, detection and classification of bias types in RNA-seq data, fast run-times, and small memory footprint.

For the initial release of the software, Lexogen is offering free licenses to academic users that will be valid until the end of the year.

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.