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Lexogen Small RNA-seq Library Prep Kit

Lexogen has launched a small RNA-seq library prep kit that is compatible with Illumina's sequencing instruments. Customers can work directly from total RNA or enriched small RNA from a variety of sources, including liquid biopsies, sorted cells, and tissues. In addition, inputs can range from 50 picograms to 1,000 nanograms of RNA. The workflow takes five hours with one hour of hands-on time. The kit comes with up to 96 unique barcodes. 

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.