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Leica Biosystems/Advanced Cell Diagnostics Aperio RNA ISH Algorithm

Leica Biosystems and Advanced Cell Diagnostics (a Bio-Techne brand) have announced the availability of the Aperio RNA ISH algorithm for use with ACD's RNAscope ISH assays.

This new offering builds on an existing collaboration between the companies to automate ACD's RNAscope assays on the Leica Biosystems BOND RX research staining platform. The new RNA ISH algorithm completes the automated RNA ISH workflow for researchers performing the RNAscope assay on the BOND RX, the companies said.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.