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KbioBox Bioinformatics Portal

KBioBox has released the KbioBox bioinformatics portal that includes a “3 click” gene editing off target analysis program and a “3 Click” gene edit biodesign program. The gene edit off target analysis solution identifies off targets in whole genomes while the gene edit design analysis solution provides top ten biodesigns based on input information. Both solutions return simple annotated reports that include intuitive visualizations, locus information, and whole-genome off target analysis for designs.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.