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JN Medsys Clarity Plus+

JN Medsys has launched the next generation of its digital PCR system, featuring more than 40,000 partitions and 4- to 6- colour detection channels. The new system offers better specifications over the firm's Clarity system, featuring improved consumables providing at least 4 times more partitions and employing ultra-high density chips that can generate more than 40,000 partitions per reaction to provide greater dynamic range and better accuracy.  The increase in partitions is also designed around the same footprint as the original system, such that the new tube-strips still fit conventional thermal cyclers to allow up to 96 reactions per run. The new system also comes with a more powerful reader equipped with a 4- to 6-colour detection system to increase detection throughput in digital PCR. It can now detect up to 384 or 576 different targets per run.
The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

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The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.