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Integrated DNA Technologies xGen Prism DNA Library Prep Kit

Integrated DNA Technologies (IDT), a Danaher company, has launched the xGen Prism DNA Library Prep Kit, which is designed for challenging and low-quality samples. The kit can convert cell-free DNA and DNA from formalin-fixed paraffin-embedded tissue into high-quality next-gen sequencing libraries. It greatly reduces adapter dimers and uses unique molecular identifiers (UMIs) for enhanced error correction.

The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.