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Integrated DNA Technologies xGen Exome Research Panel

Integrated DNA Technologies has launched the xGen Exome Research Panel for insightful analysis of the human exome via next-generation sequencing. The panel includes a total of 429,826 probes that span 39 Mb of the human genome, providing deep uniform coverage of 19,363 genes. Each probe within the panel is individually synthesized and undergoes a rigorous manufacturing and quality-assessment process in accordance with GMP standards. Missing or truncated probes are identified by mass spectrometry and OD measurements and are eliminated before pooling, providing a unique advantage over array-derived probe pools. The approach selects for full-length probes, enabling highly uniform coverage. Scientists using the xGen Exome Research Panel with xGen Lockdown Reagents and the optimized protocol can now obtain reliable and reproducible exome data in a single day, IDT said in a statement. 

The Scan

Booster Push

New data shows a decline in SARS-CoV-2 vaccine efficacy over time, which the New York Times says Pfizer is using to argue its case for a booster, even as the lower efficacy remains high.

With Help from Mr. Fluffington, PurrhD

Cats could make good study animals for genetic research, the University of Missouri's Leslie Lyons tells the Atlantic.

Man Charged With Threatening to Harm Fauci, Collins

The Hill reports that Thomas Patrick Connally, Jr., was charged with making threats against federal officials.

Nature Papers Present Approach to Find Natural Products, Method to ID Cancer Driver Mutations, More

In Nature this week: combination of cryogenic electron microscopy with genome mining helps uncover natural products, driver mutations in cancer, and more.