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Integrated DNA Technologies NGS Discovery Pools

Integrated DNA Technologies this week launched its NGS Discovery Pools, individually synthesized, 5'-biotinylated oligo pools designed to enable researchers to rapidly build custom panels at a fraction of the cost compared to conventional panels. According to the firm, the NGS Discovery Pools offer the quality of individual synthesis at a speed and scale needed for discovery in precision medicine. It also noted that the new pools will enable its customers to use its "high-quality capture technology for smaller projects and in earlier stages where content may still be changing, allowing for a smooth transition to Lockdown Probes as projects are scaled up and validated for clinical use." The firm's xGen Lockdown Probes are already commercially available for target capture in clinical sequencing applications.

The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.