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Integrated DNA Technologies Ambient Temperature PrimeTime Gene Expression Master Mix

Integrated DNA Technologies has developed a master mix for probe-based qPCR assays that is stable for ambient shipping. The company's PrimeTime Gene Expression Master Mix is the only widely distributed commercial master mix shipped in solution at ambient temperature. Under these conditions, the master mix, which is compatible with a wide range of real-time PCR instruments, continues to deliver consistent, high-quality results, the company said. IDT expects savings of approximately 33 tons (US) in total package weight, 28.5 tons in dry ice, and 4,700 square feet of landfill waste during the course of a typical year.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.