Integrated DNA Technologies Alt-R S.p. HiFi Cas9 Nuclease 3NLS Enzyme
Integrated DNA Technologies has launched the Alt-R S.p. HiFi Cas9 Nuclease 3NLS enzyme, a Cas9 enzyme variant that extensively reduces off-target effects in CRISPR genome editing without compromising on-target activity. This enzyme is a recombinant S. pyogenes Cas9 mutant that improves specificity while maintaining a high editing efficiency similar to wild-type Cas9, the company said.