Qiagen and Inova Translational Medicine Institute have announced the commercial launch of Inova Genomes, a database of ethnically, phenotypically, and ancestrally diverse whole genome sequence data from more than 2,800 families.
Qiagen will exclusively distribute the database, which contains more than 7,000 whole genomes. These datasets have been annoted with electronic health record information including bifurcation of normal vs. disease patients with high-level diagnosis as well as race, ethnicity/ancestry, and demographic information. The database also includes genotype, haplotype, longitudinal data, and pedigree information; while RNA-seq, miRNA, and methylation expression data are available for a subset of individuals. Therapeutic areas covered by the resource focus on pulmonary, gastrointestinal, genitourinary, cardiac, hematological, musculoskeletal and connective, endocrine and immunity, neoplasms, neurological disorders, microbial infection, dermatological, and ophthalmological systems.
Qiagen is offering standard and premium subscription options for Inova Genomes. A standard subscription provides access to VCF data annotated with detailed clinical information from de-identified electronic health records and is accessible only via Ingenuity Variant Analysis and CLC Biomedical Genomics Workbench. Premium subscriptions cover access to the full VCF, survey information on nutrition, environment, family history, stress and electronic health record data, BAM files, miRNA, RNA-seq and methylation data, and eligibility for access to biobanked samples and patient re-contact rights for trial recruitment.