IncellDx OncoTect IO Lung Kit
IncellDx has launched the CE-IVD marked OncoTect iO Lung kit, a flow cytometry based assay. The kit incorporates a non-enzymatic single cell tissue homogenization process, using incellPREP, for unfixed tumor biopsy samples, labels cell suspensions with antibodies to CD45, CD8, CD3, PD-L1, stained with a Cell Cycle Dye, and then analyzes samples via flow cytometry. This allows researchers to enumerate the immune and tumor cell populations, quantify the percent of cells expressing PD-L1, and quantify PD-L1 receptor expression across each cell type. The assay also quantifies tumor infiltrating lymphocytes and quantification of PD-L1 expression at various stages of the tumor cell cycle.