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Illumina NovaSeq S4 Flow Cell, Xp Workflow

Illumina has launched its S4 flow cell and reagent kit for its NovaSeq 6000 next-generation sequencing instrument and plans to launch its NovaSeq Xp workflow before the end of the year.

The S4 flow cell can deliver up to 6 terabases of data, equivalent to up to 48 human genomes or 384 exomes, in two days. The Xp workflow includes the Xp flow cell loading dock and reagents and enables users to load libraries directly onto individual flow cell lanes, which enables users to mix library types or different approaches for sample indexing. 

The Scan

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.

Seagull Microbiome Altered by Microplastic Exposure

The overall diversity and the composition at gut microbiome sites appear to coincide with microplastic exposure and ingestion in two wild bird species, according to a new Nature Ecology and Evolution study.

Study Traces Bladder Cancer Risk Contributors in Organ Transplant Recipients

In eLife, genome and transcriptome sequencing reveal mutation signatures, recurrent somatic mutations, and risky virus sequences in bladder cancers occurring in transplant recipients.

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.