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IDT Ultramer DNA and RNA Oligonucleotides

IDT has launched its Ultramer DNA and RNA oligonucleotides. The Ultramer DNA oligos are 45 to 200 nucleotides in length, available in single- or double-stranded format, and are provided deprotected and desalted. The Ultramer RNA oligos are long, single-stranded RNA of 60 to 120 nucleotides. Each oligo is assessed by mass spectrometry to verify sequence integrity using IDT's proprietary electrospray ionization method, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.