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IDT Ultramer DNA and RNA Oligonucleotides

IDT has launched its Ultramer DNA and RNA oligonucleotides. The Ultramer DNA oligos are 45 to 200 nucleotides in length, available in single- or double-stranded format, and are provided deprotected and desalted. The Ultramer RNA oligos are long, single-stranded RNA of 60 to 120 nucleotides. Each oligo is assessed by mass spectrometry to verify sequence integrity using IDT's proprietary electrospray ionization method, the company said.

The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.