Skip to main content
Premium Trial:

Request an Annual Quote

Human Longevity Oncology Genomics Products

Human Longevity has launched an oncology genomics programs, through which it is offering comprehensive whole-germline and tumor genome analysis, as well as tumor and germline exome analysis products.

With HLI's comprehensive whole-germline and cancer genome product, a patient's germline is sequenced to 30x coverage and compared to their tumor genome which will be sequenced to 90x coverage. The team employs RNAseq technology on tumors to understand the expression of mutated genes, and ImmunoSeq to sequence the patient's T cell repertoire. HLI is also testing liquid biopsy technology to detect circulating free tumor DNA and circulating tumor cells. 

The output of the sequencing efforts is a fully annotated genome report on all findings for patients and their clinicians which compares the patient's cancer and germline genomes. The analysis provides insight into tumor mutations, which can guide treatment decisions including immunotherapy, targeted molecular therapies, and clinical trials that might be of value to the patient.

The Scan

Driving Malaria-Carrying Mosquitoes Down

Researchers from the UK and Italy have tested a gene drive for mosquitoes to limit the spread of malaria, NPR reports.

Office Space to Lab Space

The New York Times writes that some empty office spaces are transforming into lab spaces.

Prion Pause to Investigate

Science reports that a moratorium on prion research has been imposed at French public research institutions.

Genome Research Papers on Gut Microbe Antibiotic Response, Single-Cell RNA-Seq Clues to Metabolism, More

In Genome Research this week: gut microbial response to antibiotic treatment, approach to gauge metabolic features from single-cell RNA sequencing, and more.