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HTG Molecular EdgeSeq Reveal

Jan 16, 2019

HTG Molecular today launched its HTG EdgeSeq Reveal software. According to the firm, the software streamlines biomarker data analysis from samples analyzed with the HTG EdgeSeq Precision Immuno-Oncology Panel on its EdgeSeq system. When used with the panel, the software allows applications including immunophenotyping of tumor infiltration lymphocytes, monitoring of immunotherapy response biomarkers, and elucidating immune-escape mechanisms know to drive disease progression. The firm noted that users will be able to conduct molecular profiling using a wide variety of sample types, potentially allowing them to support translational applications and determine potential biomarkers for companion diagnostic development. 

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Jul 22, 2019

Clear Labs Clear Safety Listeria, Environmental Mapping Testing

Menlo Park, California-based Clear Labs has launched new Listeria testing and environmental mapping capabilities on its Clear Safety next generation sequencing platform.

According to Clear Labs, Clear Safety now catalogs the genetic "fingerprint" of a Listeria sample and compares it to the fingerprints of Listeria previously encountered within a company. The platform can now detect, speciate, and characterize up to seven Listeria species ( monocytogenes, grayi, innocua, ivanovii marthii, seeligeri, and welshimeri) in a single analysis.

Clear Labs also noted that researchers can use the platform's similarity analysis to distinguish resident from transient subtypes of Listeria in the food manufacturing environment, which groups samples containing Listeria with matching fingerprints and tags them with metadata including location, date, and time. The firm's environmental mapping tool then overlays Listeria contamination on a facility map, allowing the team to track the flow of particular subtypes of Listeria through a facility over time. 

Jul 18, 2019

Menarini Silicon Biosystems VRNxT Volume Reduction Tool

Italy-based Menarini Silicon Biosystems has launched its new VRNxT automated volume reduction instrument, which removes manual sample reduction steps in cellular biology workflows. The sample prep firm said that the instrument reduces pipetting steps by using rotational motion to reduce hands-on time up to 90 percent and eliminate operator variability. The system can simultaneously process up to four samples and reduces sample volume to about 12.5 μL in 25 seconds and approximately 2 μL in about eight seconds. Menarini claims the tool will add precision and accuracy to rare-cell and single-cell analysis, minimizing the loss of samples and increasing workflow throughput. While the system has been developed to standardize Menarini's DEPArray's workflow, the firm said that researchers can use the tool for broader applications in volume reduction.


Jul 17, 2019

3M STEC Tests

3M has introduced two genetic assays for food safety testing that detect Shiga toxin-producing E. coli. The assays are compatible with the St. Paul, Minnesota-based firm's loop-mediated isothermal amplification (LAMP) instrument, the 3M Molecular Detection System.

The 3M Molecular Detection Assay 2 - STEC Gene Screen (stx and eae) detects the genes for Shiga toxin types 1 and 2, in addition to the intimin gene that allows the bacteria to attach to intestinal cells. The firm's 3M Molecular Detection Assay 2 - STEC Gene Screen (stx) specifically detects Shiga toxin genes.

Jul 15, 2019

NanoString Alzheimer’s Disease Research Panels

Seattle-based NanoString Technologies has developed a set of new nCounter gene expression panels for use in Alzheimer's disease research, which it created and tested in collaboration with the MODEL-AD consortium. The two panels — one for use in mouse studies and another for human studies — measure the expression of 770 genes covering 30 modules discovered in a recent study of human brain tissue. The firm noted that both panels are available for purchase through its website.

Jul 12, 2019

HTG Molecular EdgeSeq Data Analytics Software Version 1.2

HTG Molecular Diagnostics has released an updated version of its HTG EdgeSeq Reveal data analytics software. According to the firm, the software allows customers to streamline sample analysis processed on the HTG EdgeSeq platform. The version 1.2 update contains improved functionality, offering data analysis from the firm's HTG EdgeSeq Precision Immuno-Oncology Panel, the HTG EdgeSeq Oncology Biomarker Panel, and the HTG EdgeSeq Mouse mRNA Tumor Response Panel.

Jul 11, 2019

Co-Diagnostics Vector Smart NAM Test

Co-Diagnostics has launched its Vector Smart NAM test, which the firm said can be used to identify the presence of West Nile virus, St. Louis encephalitis, and western equine encephalitis in mosquito populations. According to Co-Diagnostics, the assay uses multiplex PCR to help centers identify locations of the diseases. 

Jul 11, 2019

Circulomics Short Read Eliminator XS, XL

Circulomics has launched two new versions of its Short Read Eliminator kit for the depletion of short DNA fragments from high molecular weight DNA samples. The Short Read Eliminator XS kit depletes DNA up to 10 kb in size and the Short Read Eliminator XL kit DNA up to 40 kb. While Circulomics designed the kits for use with its Nanobind DNA extraction kits, researchers can also use them with other DNA extraction methods.

Jul 11, 2019

Bio-Techne RNAscope HiPlex Assay

Bio-Techne released its multiplex in situ hybridization RNAscope HiPlex Assay for tissues. It enables researchers to gain insights into cellular mechanisms and functions by combining a simplistic workflow with the capability of simultaneously detecting up to twelve RNA targets, the firm said.

The research-use-only assay is an expansion of the Advanced Cell Diagnostics RNAscope platform, an advanced in situ hybridization system that enables visualization of single-molecule gene expression with single-cell resolution directly in intact tissues.

Jul 02, 2019

ZeptoMetrix NATtrol Respiratory Verification Panel

ZeptoMetrix has released the NATtrol Respiratory Verification Panel, a 20-member respiratory panel for use by laboratories in QC applications with molecular diagnostics for infectious disease testing. ZeptoMetrix was founded in 1999 and is based in Buffalo, New York.

Jul 01, 2019

Cellecta Dual-sgRNA Libraries

Cellecta has commercially launched its dual-sgRNA libraries designed for CRISPR activation (CRISPRa) and CRISPR interference/repression (CRISPRi) genetic screens. With the modified systems, the firm said it has re-engineered the standard knockout capacity to modulate gene activitiy. The variations extend the types of genetic screenings possible. 

According to Cellecta, its dual-sgRNA CRISPRa and CRISPRi libraries improve single-sgRNA library activity because each construct expresses two different sgRNA binding distinct sites on the promoter of each gene target. The firm believes this advantage increases the likelihood that each targeted gene will be activated or repressed above a given threshold when compared to libraries that only have a single sgRNA targeting a gene promoter. 

Jun 28, 2019

23andMe MUTYH-Associated Polyposis Report

23andMe has launched a new genetic health risk report for MUTYH-Associated Polyposis (MAP), one of three main hereditary colorectal cancer syndromes. According to the firm, the report examines two genetic variants in the MUTYH gene, Y179C and G396D, associated with MAP. The firm will offer the report to new Health + Ancestry Service customers as well as existing 23andMe Health + Ancestry Service customers genotyped on its most recent platforms.

Jun 28, 2019

BillionToOne Unity Prenatal Screen

BillionToOne has commercially launched its Unity prenatal screening assay. According to BillionToOne, the assay is powered by its molecular counting technology and is the only prenatal screen that tests cell-free fetal DNA for cystic fibrosis, spinal muscular atrophy, and sickle cell disease using only one tube of the mother's blood. The firm said it will make the test available at select clinics through its early access program, with plans for a broader commercial launch later this year. 

Jun 26, 2019

AutoGen Xtract 16+

AutoGen has launched its Xtract 16+ system, which it said provides fast and high-quality DNA or RNA from molecular diagnostic, biological, clinical, and forensic sample types. According to AutoGen, the instrument can simultaneously process between 1-16 samples. The Xtract 16+ also provides full traceability of kits and samples through real-time, app-based monitoring, which automatically generates reports for LIS/LIMS. 

Jun 26, 2019

Thermo Fisher Scientific Invitrogen Collibri DNA Library Prep Kits

Thermo Fisher Scientific has launched several Invitrogen Collibri DNA Library Prep kits for use with high-throughput Illumina sequencing systems. The kits contain a tracking dye to visualize the library prep process and to show that reagents have been properly mixed. The dyes do not interfere with enzymatic reactions and do not affect the sequencing results. Four versions of the kit are available, for either physically sheared or enzymatically sheared DNA, and involving either PCR or no PCR. All kits contain adapters with unique dual indexes or combinatorial dual indexes that enable up to 24 or 96 samples to be pooled for sequencing.

Jun 26, 2019

Porvair Sciences Drosophila ChIP Kits

Porvair Sciences has launched its commercial ChIP kit range dedicated to Drosophila. The new kits deliver high-quality ChIP-ready chromatin from tissue from as little as five Drosophila specimens. According to Porvair, the new kits offer improved sensitivity. The new Chromatrap range includes Drosohila UniqSeq, ChIP-Seq, Antibodies, and Primer Sets. 

The Guardian reports that some UK physicians are calling for increased regulation of direct-to-consumer genetic tests.

US tax agency says 23andMe's genetic health test can be claimed as a medical expense for tax purposes, the Wall Street Journal reports.

Two Democratic lawmakers argue at USA Today that independent science is under attack by the Trump Administration.

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