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HTG Molecular Diagnostics EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin Assay

HTG Molecular Diagnostics has introduced the HTG EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin assay. The test, which is for research use only, classifies DLBCL into one of the two major subtypes: activated B-cell-like or germinal center B-cell-like. The assay is performed on the automated HTG EdgeSeq system, and couples the company's proprietary nuclease protection chemistry with next-generation sequencing. The test was validated on more than 250 cases previously subtyped through microarray-based gene expression profiling, HTG said.

The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.