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HTG Molecular Diagnostics EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin Assay

HTG Molecular Diagnostics has introduced the HTG EdgeSeq Diffuse Large B-Cell Lymphoma Cell of Origin assay. The test, which is for research use only, classifies DLBCL into one of the two major subtypes: activated B-cell-like or germinal center B-cell-like. The assay is performed on the automated HTG EdgeSeq system, and couples the company's proprietary nuclease protection chemistry with next-generation sequencing. The test was validated on more than 250 cases previously subtyped through microarray-based gene expression profiling, HTG said.

The Scan

And Back

The New York Times reports that missing SARS-CoV-2 genome sequences are back in a different database.

Lacks Family Hires Attorney

A lawyer for the family of Henrietta Lacks plans to seek compensation from pharmaceutical companies that have used her cancer cells in product development, the Baltimore Sun reports.

For the Unknown

The Associated Press reports that family members are calling on the US military to use new DNA analysis techniques to identify unknown sailors and Marines who were on the USS Arizona.

PLOS Papers on Congenital Heart Disease, COVID-19 Infection Host MicroRNAs, Multiple Malformation Mutations

In PLOS this week: new genes linked to congenital heart disease, microRNAs with altered expression in COVID-19, and more.