Horizon Discovery's Synthetic Plasma cfDNA Reference Standard
Horizon Discovery Group has launched a new tool called the HDx cell-free DNA Reference Standard in Synthetic Plasma. According to the company, the new reference set addresses challenges in extracting DNA for liquid biopsy testing, helps to ensure that an assay is not over or under loaded, and allows users to better control variation in their tests. The set contains eight cancer-relevant mutations including BRAF, EGFR, KRAS, NRAS, and PIK3CA at 5 percent, 1 percent, and 0.1 percent allelic frequencies. Because the reference is engineered in plasma, mimicking actual human material, users can gain better understanding of assay performance from extraction and quantification through to analysis and informatics, Horizon added.