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Horizon Discovery Reference Standards for Biocartis Idylla MSI Assay

Horizon Discovery has launched a set of precisely defined cell line-derived reference standards to support Biocartis' recently launched Idylla microsatellite instability (MSI) Assay. The Idylla MSI Assay (RUO) allows for qualitative detection of a novel panel of seven monomorphic homopolymer biomarkers to identify human cancers with microsatellite instability, in a fully automated manner. The assay uses formalin-fixed, paraffin-embedded tissue sections from human cancer samples, and extracts, amplifies, and analyzes the nucleic acids.

Horizon's newly developed MSI FFPE reference standards, which were developed in a collaboration between the two companies, enable validation and routine monitoring of MSI testing on the Idylla platform. The reference standard material consists of a pair of FFPE sections, positive and negative for all seven MSI markers, providing a whole-process control that closely mimics a real FFPE sample. The reference standard is manufactured under ISO13485 at Horizon.

The Scan

Not Yet a Permanent One

NPR says the lack of a permanent Food and Drug Administration commissioner has "flummoxed" public health officials.

Unfair Targeting

Technology Review writes that a new report says the US has been unfairly targeting Chinese and Chinese-American individuals in economic espionage cases.

Limited Rapid Testing

The New York Times wonders why rapid tests for COVID-19 are not widely available in the US.

Genome Research Papers on IPAFinder, Structural Variant Expression Effects, Single-Cell RNA-Seq Markers

In Genome Research this week: IPAFinder method to detect intronic polyadenylation, influence of structural variants on gene expression, and more.