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Horizon Discovery EGFR Multiplex cfDNA Reference Standard

Horizon Discovery has launched a new cell line-derived EGFR Multiplex cell-free DNA reference standard, which allows labs and assay developers to optimize, validate and routinely monitor performance of PCR assays, NGS tests, and other novel liquid biopsy tests designed to detect EGFR mutations in cfDNA.

The new referene standard covers ten of the most clinically relevant mutations that predict responsiveness to EGFR tyrosine kinase inhibitors, including T790M, L858R, C797S and E746-A750del. Additionally, variants have been carefully selected to represent a mix of different mutation types that can be challenging for laboratories to detect.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.