Horizon Discovery Edit-R CRISPRa Arrayed CRISPR RNA Libraries

Horizon Discovery has released the Edit-R CRISPRa arrayed crRNA (CRISPR RNA) libraries, the newest addition to its CRISPR activation reagent platform from the recently acquired Dharmacon business. The new libraries can be used for drug discovery, pathway analysis, and disease progression studies, Horizon said. Edit-R synthetic crRNA arrayed libraries enable one-gene-per-well investigation. They also trigger the endogenous gene's expression, transcribing the gene in its native form.

The Edit-R CRISPRa portfolio includes catalogue libraries for popular human and mouse gene families, such as ubiquitin enzymes, transcription factors, and kinases, in addition to druggable gene targets and the whole human genome. Bespoke collections are also available to support researchers working with a specialized gene target list.