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Genomenon Mastermind Search Engine

Genomenon has announced the limited availability of a free version of its Mastermind genomic search engine for clinical, research, and academic institutions. The free offering lacks some of the features of Mastermind Professional Edition, including genomic data analysis services and workflow automation tools, but it has the same targeted search of genomic research that filters out results not clinically relevant to those interested in genetic relationships to specific diseases. For now, Mastermind Free Edition is available by invitation only. 

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.