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Furukawa Electric Single Cell Hunter

Furukawa Electric has launched the Single Cell Hunter, a microchip-based automated live cell high-throughput screening system. Single Cell Hunter analyzes live cells on a microchip within a temperature-adjustable chamber to catch the responses of stimulated cells under near-physiological conditions and identify them in a time-lapse mode, which enables accurate evaluation of the real potential of each cell. The system features standard, pre-coated microchips for dynamic identification and recovery of fluorescence-labeled cells, or for fluorescence-linked immunosorbent assays for the identification of the cells that have an ability to secrete antibodies or specific antigen proteins. The platform also features multi-color screening, and AI-based high-precision cell-friendly pick-up and drop-off technology, which enables recovery of even a single yeast cell as small as 3 μm in diameter from a 10-μm microwell.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.