Fluxion Biosciences Spotlight Liquid Biopsy NGS Panels
Fluxion Biosciences has launched three new targeted next-generation sequencing liquid biopsy panels, including Spotlight Myeloid, Spotlight EGFR, and the Spotlight TP53. The Alameda, California-based firm's Spotlight Myeloid panel includes 478 amplicons that cover 23 clinically relevant genes implicated in acute myeloid leukemia, myelodysplastic syndrome, and myeloproliferative neoplasms. The Spotlight EGFR panel offers contiguous coverage of EGFR and hotspot coverage of BRAF, KRAS, and NRAS mutations, using a 17-amplicon design to generate multiplex libraries compatible with Illumina sequencing platforms. The Spotlight TP53 panel uses 21 amplicons with an average size of 140 base pairs, providing coverage of all TP53 coding regions. According to Flux Bio, the panels have been validated and come with its ERASE-Seq variant caller.