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Fluidigm Advanta Immuno-Oncology Gene Expression Assay

Fluidigm has launched the Advanta Immuno-Oncology Gene Expression Assay, a research-use-only qPCR assay that enables interrogation of tumor immunobiology using Fluidigm's microfluidic technology. Designed for use with the Biomark HD system, the assay detects 170 gene expression markers involved in checkpoint therapeutic response from FFPE and fresh frozen tumor samples. The assay can analyze biomarkers across defined T cell subsets, immune regulation, immune cell fate, cytokines, chemokines, and more, and can enable translational researchers to accelerate the development of checkpoint immunotherapies and to identify predictive biomarker signatures for therapeutic response.

Fluidigm said that the product is available as a two-panel set. The first panel includes 91 key markers of tumor immune response that were previously shown in a multicenter international clinical trial to inform tumor progression and checkpoint therapeutic response. The second panel includes 74 additional immuno-oncology markers and 17 open assay inlets for additional customization. Both panels contain the same five reference genes and can be purchased and used together or separately.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.