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FactBio's Kusp Platform

FactBio has updated Kusp, its commercial data curation platform. Version 1.1 includes a new resource mapping module that lets users map reference entities, such as those in ontologies and biological databases, to external reference entities. The platform also includes improved search and annotation algorithms, an improved interface that lets users personalize and track their search activities, and it supports faster data uploads. Furthermore, the platform now features over 200,000 ontology classes including more plant ontologies and UniProt proteins. 

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.