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Exiqon ExiLERATE LNA

Exiqon has launched a quantitative PCR product portfolio, ExiLERATE LNA, enabling real-time PCR analysis of mRNAs and long non-coding RNA. The suite of products supports sample isolation, cDNA generation, real-time PCR amplification, and detection, and is compatible with all major real-time PCR instruments. It includes endogenous controls and supports custom assay design facilitated by an assay design tool called XploreRNA.

The Scan

Transcriptomic, Epigenetic Study Appears to Explain Anti-Viral Effects of TB Vaccine

Researchers report in Science Advances on an interferon signature and long-term shifts in monocyte cell DNA methylation in Bacille Calmette-Guérin-vaccinated infant samples.

DNA Storage Method Taps Into Gene Editing Technology

With a dual-plasmid system informed by gene editing, researchers re-wrote DNA sequences in E. coli to store Charles Dickens prose over hundreds of generations, as they recount in Science Advances.

Researchers Model Microbiome Dynamics in Effort to Understand Chronic Human Conditions

Investigators demonstrate in PLOS Computational Biology a computational method for following microbiome dynamics in the absence of longitudinally collected samples.

New Study Highlights Role of Genetics in ADHD

Researchers report in Nature Genetics on differences in genetic architecture between ADHD affecting children versus ADHD that persists into adulthood or is diagnosed in adults.