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Era7 V4V6 Taxonomic Profiling Service

Spanish-based Era7 has launched its V4V6 taxonomic profiling service for amplicon analysis. According to the firm, the approach uses optimal primers located in 16S regions highly conserved in bacteria and archaea. Using 300-cycle Illumina reagents, the approach sequences V4 and V6 variable regions and their flanking sequences. Era7 said that it has designed the primers to cover all sequences included in its 16SDB7 database. 

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.