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EntroGen Multiplexed Leukemia Translocation Panel

EntroGen has launched the Leukemia Translocation panel. It is a multiplexed, one-step real-time PCR assay that detects eleven variants in 6 common leukemia associated translocations simultaneously. The panel detects and identifies AML1-ETO, CBFB-MYH11, MLL-AF4, TEL-AML1, E2A-PBX1, and PML-RARA fusion gene transcripts from total RNA isolated from blood or bone marrow. The product is compatible with several leading multi-channel real-time PCR instruments capable of detecting four commonly used fluorescent probes and produces results in just 90 minutes, the company said. It can also be run together with the company's p190 and p120 real-time PCR kits for a comprehensive test for fusion genes implicated in CML, ALL, APL, and AML, the company said.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.