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Ensembl Genomes 28

Ensembl Genomes 28 is now available. This release features updates to version 81 of the Ensembl platform across all divisions with a total of of 23,636 genomes from 4,991 species. It also includes annoation updates for Schizosaccharomyces pombe (fission yeast); and recalculated protein domains for Ensembl protists, metazoa, fungi and plants using the latest version of InterProScan.

The Scan

RNA Editing in Octopuses Seems to Help Acclimation to Shifts in Water Temperature

A paper in Cell reports that octopuses use RNA editing to help them adjust to different water temperatures.

Topical Compound to Block EGFR Inhibitors May Ease Skin Toxicities, Study Finds

A topical treatment described in Science Translational Medicine may limit skin toxicities seen with EGFR inhibitor therapy.

Dozen Genetic Loci Linked to Preeclampsia Risk in New GWAS

An analysis of genome-wide association study data in JAMA Cardiology finds genetic loci linked to preeclampsia that have ties to blood pressure.

Cancer Survival Linked to Mutational Burden in Pan-Cancer Analysis

A pan-cancer paper appearing in JCO Precision Oncology suggests tumor mutation patterns provide clues for predicting cancer survival that are independent of other prognostic factors.