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Empirical Bioscience EB Pure Agarose Gel Extraction Kit

Empirical Bioscience has introduced the EB Pure Agarose Gel Extraction Kit, which is designed to isolate small DNA fragments (70 bp to 20 kb) from agarose gel in 15 minutes. The system specifically but reversibly binds DNA or RNA under optimized conditions, allowing proteins and other contaminants to be removed. Empirical claims the process will help guarantee consistent recovery rates in more than 85 percent of cases, while simultaneously removing primer-dimers, primers, nucleotides, proteins, salt, agarose, ethidium bromide, and other impurities. The extracted DNA can be used in most applications including ligations, PCR, sequencing, restriction digestion, or various labeling reactions, the firm said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.